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Data availability All data generated or analyzed during this study are included in this published article (and its Supplementary Information file)

10.1371/journal.pone.0163806 144 ZhangY

Stimulating the vagus nerve, the tenth cranial nerve that plays a central role in regulating the parasympathetic nervous system, can significantly reduce blood-brain barrier permeability and enhance concussion rehabilitation outcomes through targeted concussion therapy techniques